Kaposi’s sarcoma (KS) is a rare type of cancer that often presents as purplish, reddish, or brown lesions in the mouth or on other parts of the body. In oral Kaposi’s sarcoma, these lesions commonly appear on the palate, gums, or inside the cheeks. They are caused by an infection with human herpesvirus 8 (HHV-8) and are most commonly associated with weakened immune systems, such as in individuals living with HIV/AIDS. While these lesions may be painless initially, they can become tender, bleed, or interfere with eating and speaking as they progress. Early diagnosis and treatment are essential, and options may include antiretroviral therapy, chemotherapy, or localized treatments to manage symptoms and improve quality of life.